Scopolamine Treatment and Muscarinic Receptor Subtype-3 Gene Ablation Augment Azoxymethane-Induced Murine Liver Injury

Previous work suggests that vagus nerve disruption reduces hepatocyte and oval cell expansion after liver injury. The role of postneuronal receptor activation in response to liver injury has not been ascertained. We investigated the actions of scopolamine, a nonselective muscarinic receptor antagoni...

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Autori principali: Khurana, Sandeep, Shah, Nirish, Cheng, Kunrong, Shiu, Brian, Samimi, Roxana, Belo, Angelica, Shant, Jasleen, Drachenberg, Cinthia, Wess, Jürgen, Raufman, Jean-Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
Soggetti:
Toxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879938/
https://ncbi.nlm.nih.gov/pubmed/20197374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.165118
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