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Scopolamine Treatment and Muscarinic Receptor Subtype-3 Gene Ablation Augment Azoxymethane-Induced Murine Liver Injury

Previous work suggests that vagus nerve disruption reduces hepatocyte and oval cell expansion after liver injury. The role of postneuronal receptor activation in response to liver injury has not been ascertained. We investigated the actions of scopolamine, a nonselective muscarinic receptor antagoni...

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Detalhes bibliográficos
Main Authors: Khurana, Sandeep, Shah, Nirish, Cheng, Kunrong, Shiu, Brian, Samimi, Roxana, Belo, Angelica, Shant, Jasleen, Drachenberg, Cinthia, Wess, Jürgen, Raufman, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879938/
https://ncbi.nlm.nih.gov/pubmed/20197374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.165118
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