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Scopolamine Treatment and Muscarinic Receptor Subtype-3 Gene Ablation Augment Azoxymethane-Induced Murine Liver Injury

Previous work suggests that vagus nerve disruption reduces hepatocyte and oval cell expansion after liver injury. The role of postneuronal receptor activation in response to liver injury has not been ascertained. We investigated the actions of scopolamine, a nonselective muscarinic receptor antagoni...

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Détails bibliographiques
Auteurs principaux: Khurana, Sandeep, Shah, Nirish, Cheng, Kunrong, Shiu, Brian, Samimi, Roxana, Belo, Angelica, Shant, Jasleen, Drachenberg, Cinthia, Wess, Jürgen, Raufman, Jean-Pierre
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879938/
https://ncbi.nlm.nih.gov/pubmed/20197374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.165118
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