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Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion

Muscarinic receptors (CHRM) are overexpressed in colon cancer. To explore a role for muscarinic receptor signaling in colon cancer metastasis, we used human H508 and HT29 colon cancer cells that coexpress epidermal growth factor (ERBB) and CHRM3 receptors. In a wound closure model, following 8-h inc...

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Detalhes bibliográficos
Main Authors: Belo, Angelica, Cheng, Kunrong, Chahdi, Ahmed, Shant, Jasleen, Xie, Guofeng, Khurana, Sandeep, Raufman, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094147/
https://ncbi.nlm.nih.gov/pubmed/21273532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00306.2010
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