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Genetic Ablation of M(3) Muscarinic Receptors Attenuates Murine Colon Epithelial Cell Proliferation and Neoplasia
Normal colon epithelial cells express and most colon cancers over-express M(3) muscarinic receptors (M(3)R). In human colon cancer cells, post-M(3)R signaling stimulates cell proliferation. To explore the importance of M(3)R expression in vivo we used the azoxymethane (AOM)-induced colon neoplasia m...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577901/ https://ncbi.nlm.nih.gov/pubmed/18483237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6810 |
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