Genetic Ablation of M(3) Muscarinic Receptors Attenuates Murine Colon Epithelial Cell Proliferation and Neoplasia

Normal colon epithelial cells express and most colon cancers over-express M(3) muscarinic receptors (M(3)R). In human colon cancer cells, post-M(3)R signaling stimulates cell proliferation. To explore the importance of M(3)R expression in vivo we used the azoxymethane (AOM)-induced colon neoplasia m...

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Detaylı Bibliyografya
Asıl Yazarlar: Raufman, Jean-Pierre, Samimi, Roxana, Shah, Nirish, Khurana, Sandeep, Shant, Jasleen, Drachenberg, Cinthia, Xie, Guofeng, Wess, Jürgen, Cheng, Kunrong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577901/
https://ncbi.nlm.nih.gov/pubmed/18483237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6810
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