Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II

The visualization at near atomic resolution of transient substrates in the active site of enzymes is fundamental to fully understanding their mechanism of action. Here we show the application of using CO(2)-pressurized, cryo-cooled crystals to capture the first step of CO(2) hydration catalyzed by t...

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Bibliografiske detaljer
Main Authors: Domsic, John F., Avvaru, Balendu Sankara, Kim, Chae Un, Gruner, Sol M., Agbandje-McKenna, Mavis, Silverman, David N., McKenna, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576554/
https://ncbi.nlm.nih.gov/pubmed/18768466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805353200
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