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Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II

The visualization at near atomic resolution of transient substrates in the active site of enzymes is fundamental to fully understanding their mechanism of action. Here we show the application of using CO(2)-pressurized, cryo-cooled crystals to capture the first step of CO(2) hydration catalyzed by t...

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Библиографические подробности
Главные авторы: Domsic, John F., Avvaru, Balendu Sankara, Kim, Chae Un, Gruner, Sol M., Agbandje-McKenna, Mavis, Silverman, David N., McKenna, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576554/
https://ncbi.nlm.nih.gov/pubmed/18768466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805353200
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