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Tracking solvent and protein movement during CO(2) release in carbonic anhydrase II crystals
Carbonic anhydrases are mostly zinc metalloenzymes that catalyze the reversible hydration/dehydration of CO(2)/HCO(3)(−). Previously, the X-ray crystal structures of CO(2)-bound holo (zinc-bound) and apo (zinc-free) human carbonic anhydrase IIs (hCA IIs) were captured at high resolution. Here, we pr...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868437/ https://ncbi.nlm.nih.gov/pubmed/27114542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520786113 |
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