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A Short, Strong Hydrogen Bond in the Active Site of Human Carbonic Anhydrase II
The crystal structure of human carbonic anhydrase II (HCA II) obtained at 0.9 Å resolution reveals that a water molecule, termed deep water, Dw, and bound in a hydrophobic pocket of the active site forms a short, strong hydrogen bond with the zinc-bound solvent molecule, a conclusion based on the ob...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810610/ https://ncbi.nlm.nih.gov/pubmed/20000378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902007b |
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