Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II

The visualization at near atomic resolution of transient substrates in the active site of enzymes is fundamental to fully understanding their mechanism of action. Here we show the application of using CO(2)-pressurized, cryo-cooled crystals to capture the first step of CO(2) hydration catalyzed by t...

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Detalhes bibliográficos
Main Authors: Domsic, John F., Avvaru, Balendu Sankara, Kim, Chae Un, Gruner, Sol M., Agbandje-McKenna, Mavis, Silverman, David N., McKenna, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576554/
https://ncbi.nlm.nih.gov/pubmed/18768466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805353200
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