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Sarcospan reduces dystrophic pathology: stabilization of the utrophin–glycoprotein complex
Mutations in the dystrophin gene cause Duchenne muscular dystrophy and result in the loss of dystrophin and the entire dystrophin–glycoprotein complex (DGC) from the sarcolemma. We show that sarcospan (SSPN), a unique tetraspanin-like component of the DGC, ameliorates muscular dystrophy in dystrophi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575773/ https://ncbi.nlm.nih.gov/pubmed/18981229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200808027 |
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