Myogenic Akt signaling upregulates the utrophin–glycoprotein complex and promotes sarcolemma stability in muscular dystrophy

Duchenne muscular dystrophy is caused by dystrophin mutations that lead to structural instability of the sarcolemma membrane, myofiber degeneration/regeneration and progressive muscle wasting. Here we show that myogenic Akt signaling in mouse models of dystrophy promotes increased expression of utro...

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Bibliografiset tiedot
Päätekijät: Peter, Angela K., Ko, Christopher Y., Kim, Michelle H., Hsu, Nigel, Ouchi, Noriyuki, Rhie, Suhn, Izumiya, Yasuhiro, Zeng, Ling, Walsh, Kenneth, Crosbie, Rachelle H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2009
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638781/
https://ncbi.nlm.nih.gov/pubmed/18986978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn358
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