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Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice
Sarcospan (SSPN) is a core component of the major adhesion complexes in skeletal muscle, the dystrophin– and utrophin (Utr)–glycoprotein complexes (DGC and UGC). We performed a rigorous analysis of SSPN-null mice and discovered that loss of SSPN decreased DGC and UGC abundance, leading to impaired l...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459462/ https://ncbi.nlm.nih.gov/pubmed/22798625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds271 |
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