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Molecular Defects Caused by Temperature-Sensitive Mutations in Semliki Forest Virus nsP1
Alphavirus replicase protein nsP1 has multiple functions during viral RNA synthesis. It catalyzes methyltransferase and guanylyltransferase activities needed in viral mRNA capping, attaches the viral replication complex to cytoplasmic membranes, and is required for minus-strand RNA synthesis. Two te...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546902/ https://ncbi.nlm.nih.gov/pubmed/18596091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00711-08 |
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