Role for nsP2 Proteins in the Cessation of Alphavirus Minus-Strand Synthesis by Host Cells

In order to establish nonlytic persistent infections (PI) of BHK cells, replicons derived from Sindbis (SIN) and Semliki Forest (SFV) viruses have mutations in nsP2. Five different nsP2 PI replicons were compared to wild-type (wt) SIN, SFV, and wt nsPs SIN replicons. Replicon PI BHK21 cells had vira...

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Detalhes bibliográficos
Main Authors: Sawicki, Dorothea L., Perri, Silvia, Polo, John M., Sawicki, Stanley G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317508/
https://ncbi.nlm.nih.gov/pubmed/16352561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.360-371.2006
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