Alphavirus Minus-Strand RNA Synthesis: Identification of a Role for Arg183 of the nsP4 Polymerase

A partially conserved region spanning amino acids 142 to 191 of the Sindbis virus (SIN) nsP4 core polymerase is implicated in host restriction, elongation, and promoter recognition. We extended the analysis of this region by substituting Ser, Ala, or Lys for a highly conserved Arg183 residue immedia...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Fata, Cori L., Sawicki, Stanley G., Sawicki, Dorothea L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136981/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12163582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.17.8632-8640.2002
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