Molecular Defects Caused by Temperature-Sensitive Mutations in Semliki Forest Virus nsP1

Alphavirus replicase protein nsP1 has multiple functions during viral RNA synthesis. It catalyzes methyltransferase and guanylyltransferase activities needed in viral mRNA capping, attaches the viral replication complex to cytoplasmic membranes, and is required for minus-strand RNA synthesis. Two te...

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Detaylı Bibliyografya
Asıl Yazarlar: Lulla, Valeria, Sawicki, Dorothea L., Sawicki, Stanley G., Lulla, Aleksei, Merits, Andres, Ahola, Tero
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Genome Replication and Regulation of Viral Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546902/
https://ncbi.nlm.nih.gov/pubmed/18596091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00711-08
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