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Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants

We have analyzed the biochemical consequences of mutations that affect viral RNA synthesis in Semliki Forest virus temperature-sensitive (ts) mutants. Of the six mutations mapping in the multifunctional replicase protein nsP2, three were located in the N-terminal helicase region and three were in th...

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Autori principali: Balistreri, Giuseppe, Caldentey, Javier, Kääriäinen, Leevi, Ahola, Tero
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866018/
https://ncbi.nlm.nih.gov/pubmed/17202213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02078-06
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