Identification of Mutations Causing Temperature-Sensitive Defects in Semliki Forest Virus RNA Synthesis

We have sequenced the nonstructural protein coding region of Semliki Forest virus temperature-sensitive (ts) mutant strains ts1, ts6, ts9, ts10, ts11, ts13, and ts14. In each case, the individual amino acid changes uncovered were transferred to the prototype strain background and thereby identified...

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Main Authors: Lulla, Valeria, Merits, Andres, Sarin, Peter, Kääriäinen, Leevi, Keränen, Sirkka, Ahola, Tero
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395444/
https://ncbi.nlm.nih.gov/pubmed/16501123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.6.3108-3111.2006
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