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Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication

Semliki Forest virus RNA replication takes place in association with specific cytoplasmic vacuoles, derived from the endosomal apparatus. Of the four virus-encoded replicase proteins, nsP1 serves as the membrane anchor of the replication complex. An amphipathic peptide segment, G(245)STLYTESRKLLRSWH...

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Detalhes bibliográficos
Main Authors: Spuul, Pirjo, Salonen, Anne, Merits, Andres, Jokitalo, Eija, Kääriäinen, Leevi, Ahola, Tero
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797454/
https://ncbi.nlm.nih.gov/pubmed/17093195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01785-06
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