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Characterization of the cysteine protease domain of Semliki Forest virus replicase protein nsP2 by in vitro mutagenesis

The function of Semliki Forest Virus nsP2 protease was investigated by site‐directed mutagenesis. Mutations were introduced in its protease domain, Pro39, and the mutated proteins were expressed in Escherichia coli, purified and their activity in vitro was compared to that of the wild type Pro39. Mu...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Golubtsov, Andrey, Kääriäinen, Leevi, Caldentey, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118720/
https://ncbi.nlm.nih.gov/pubmed/16466719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.01.071
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