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Molecular Defects Caused by Temperature-Sensitive Mutations in Semliki Forest Virus nsP1

Alphavirus replicase protein nsP1 has multiple functions during viral RNA synthesis. It catalyzes methyltransferase and guanylyltransferase activities needed in viral mRNA capping, attaches the viral replication complex to cytoplasmic membranes, and is required for minus-strand RNA synthesis. Two te...

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Bibliografische gegevens
Hoofdauteurs: Lulla, Valeria, Sawicki, Dorothea L., Sawicki, Stanley G., Lulla, Aleksei, Merits, Andres, Ahola, Tero
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546902/
https://ncbi.nlm.nih.gov/pubmed/18596091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00711-08
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