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Fate of Minus-Strand Templates and Replication Complexes Produced by a P23-Cleavage-Defective Mutant of Sindbis Virus

SIN2V is an engineered mutant Sindbis virus (SIN) that is unable to process the P23 cleavage site in polyproteins P123 and P1234 that are translated from the genome after its entry into cells. Unlike wild-type (wt) SIN, it caused minus strands to be made continuously and replication-transcription co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mai, Junbo, Sawicki, Stanley G., Sawicki, Dorothea L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738138/
https://ncbi.nlm.nih.gov/pubmed/19515769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00056-09
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