Fate of Minus-Strand Templates and Replication Complexes Produced by a P23-Cleavage-Defective Mutant of Sindbis Virus

SIN2V is an engineered mutant Sindbis virus (SIN) that is unable to process the P23 cleavage site in polyproteins P123 and P1234 that are translated from the genome after its entry into cells. Unlike wild-type (wt) SIN, it caused minus strands to be made continuously and replication-transcription co...

Full description

Saved in:
Bibliographic Details
Main Authors: Mai, Junbo, Sawicki, Stanley G., Sawicki, Dorothea L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738138/
https://ncbi.nlm.nih.gov/pubmed/19515769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00056-09
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items