Učitavanje...
Partitioning Conformational Intermediates Between Competing Refolding and Aggregation Pathways: Insights into Transthyretin Amyloid Disease
Amyloid diseases are caused by the aberrant assembly of a protein in the extracellular space. Folded proteins are not amyloidogenic, however the native state is generally in equilibrium with a minor population of unfolded or partially folded aggregation-competent conformers outside of the cell. Unde...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2532856/ https://ncbi.nlm.nih.gov/pubmed/16342952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0511484 |
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