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Two Distinct Aggregation Pathways in Transthyretin Misfolding and Amyloid Formation
Misfolding and amyloid formation of transthyretin (TTR) is implicated in numerous degenerative diseases. TTR misfolding is greatly accelerated under acidic conditions, and thus most of the mechanistic studies of TTR amyloid formation have been conducted at various acidic pH values (2 – 5). In this s...
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| Publicado no: | Biochim Biophys Acta Proteins Proteom |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6339575/ https://ncbi.nlm.nih.gov/pubmed/30366153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2018.10.013 |
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