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Two Distinct Aggregation Pathways in Transthyretin Misfolding and Amyloid Formation

Misfolding and amyloid formation of transthyretin (TTR) is implicated in numerous degenerative diseases. TTR misfolding is greatly accelerated under acidic conditions, and thus most of the mechanistic studies of TTR amyloid formation have been conducted at various acidic pH values (2 – 5). In this s...

詳細記述

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書誌詳細
出版年:Biochim Biophys Acta Proteins Proteom
主要な著者: Dasari, Anvesh K. R., Hung, Ivan, Gan, Zhehong, Lim, Kwang Hun
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339575/
https://ncbi.nlm.nih.gov/pubmed/30366153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2018.10.013
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