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Two Distinct Aggregation Pathways in Transthyretin Misfolding and Amyloid Formation
Misfolding and amyloid formation of transthyretin (TTR) is implicated in numerous degenerative diseases. TTR misfolding is greatly accelerated under acidic conditions, and thus most of the mechanistic studies of TTR amyloid formation have been conducted at various acidic pH values (2 – 5). In this s...
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| 出版年: | Biochim Biophys Acta Proteins Proteom |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6339575/ https://ncbi.nlm.nih.gov/pubmed/30366153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2018.10.013 |
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