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Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers

Characterization of small oligomers formed at an early stage of amyloid formation is critical to understanding molecular mechanism of pathogenic aggregation process. Here we identified and characterized cytotoxic oligomeric intermediates populated during transthyretin (TTR) aggregation process. Unde...

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書目詳細資料
發表在:Sci Rep
Main Authors: Dasari, Anvesh K. R., Hughes, Robert M., Wi, Sungsool, Hung, Ivan, Gan, Zhehong, Kelly, Jeffrey W., Lim, Kwang Hun
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328637/
https://ncbi.nlm.nih.gov/pubmed/30631096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37230-1
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