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Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers

Characterization of small oligomers formed at an early stage of amyloid formation is critical to understanding molecular mechanism of pathogenic aggregation process. Here we identified and characterized cytotoxic oligomeric intermediates populated during transthyretin (TTR) aggregation process. Unde...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Dasari, Anvesh K. R., Hughes, Robert M., Wi, Sungsool, Hung, Ivan, Gan, Zhehong, Kelly, Jeffrey W., Lim, Kwang Hun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328637/
https://ncbi.nlm.nih.gov/pubmed/30631096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37230-1
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