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Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers
Characterization of small oligomers formed at an early stage of amyloid formation is critical to understanding molecular mechanism of pathogenic aggregation process. Here we identified and characterized cytotoxic oligomeric intermediates populated during transthyretin (TTR) aggregation process. Unde...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328637/ https://ncbi.nlm.nih.gov/pubmed/30631096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37230-1 |
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