WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand

Werner syndrome (WS) is a premature aging disorder caused by mutations in the WS gene (WRN). Although WRN has been suggested to play an important role in DNA metabolic pathways, such as recombination, replication and repair, its precise role still remains to be determined. WRN possesses ATPase, heli...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bukowy, Zuzanna, Harrigan, Jeanine A., Ramsden, Dale A., Tudek, Barbara, Bohr, Vilhelm A., Stevnsner, Tinna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2008
Gaiak:
Molecular Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528166/
https://ncbi.nlm.nih.gov/pubmed/18658245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn468
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