Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

BACKGROUND: Misfolding and pathological aggregation of neuronal proteins has been proposed to play a critical role in the pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) and Parkinson's disease (PD) are frequent neurodegenerative diseases of the aging population. Whil...

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Hlavní autoři: Tsigelny, Igor F., Crews, Leslie, Desplats, Paula, Shaked, Gideon M., Sharikov, Yuriy, Mizuno, Hideya, Spencer, Brian, Rockenstein, Edward, Trejo, Margarita, Platoshyn, Oleksandr, Yuan, Jason X.-J., Masliah, Eliezer
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519786/
https://ncbi.nlm.nih.gov/pubmed/18769546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003135
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