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Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP
The endoplasmic reticulum membrane protein SREBP cleavage-activating protein (Scap) senses sterols and regulates activation of sterol-regulatory element binding proteins (SREBPs), membrane-bound transcription factors that control lipid homeostasis in fission yeast and mammals. Transmembrane segments...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2515523/ https://ncbi.nlm.nih.gov/pubmed/18503029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800207-JLR200 |
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