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Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
Sterol regulatory element-binding protein (SREBP) transcription factors are master regulators of cellular lipid homeostasis in mammals and oxygen-responsive regulators of hypoxic adaptation in fungi. SREBP C-terminus binds to the WD40 domain of SREBP cleavage-activating protein (SCAP), which confers...
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| Опубликовано в: : | Cell Res |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5099872/ https://ncbi.nlm.nih.gov/pubmed/27811944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.123 |
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