Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition

The sterol regulatory element-binding protein (SREBP) and SREBP cleavage-activating protein (SCAP) are central players in the SREBP pathway, which control the cellular lipid homeostasis. SCAP binds to SREBP through their carboxyl (C) domains and escorts SREBP from the endoplasmic reticulum to the Go...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Res
Prif Awduron: Gong, Xin, Li, Jingxian, Shao, Wei, Wu, Jianping, Qian, Hongwu, Ren, Ruobing, Espenshade, Peter, Yan, Nieng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387560/
https://ncbi.nlm.nih.gov/pubmed/25771684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.32
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