Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition

The sterol regulatory element-binding protein (SREBP) and SREBP cleavage-activating protein (SCAP) are central players in the SREBP pathway, which control the cellular lipid homeostasis. SCAP binds to SREBP through their carboxyl (C) domains and escorts SREBP from the endoplasmic reticulum to the Go...

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Spremljeno u:
Bibliografski detalji
Izdano u:Cell Res
Glavni autori: Gong, Xin, Li, Jingxian, Shao, Wei, Wu, Jianping, Qian, Hongwu, Ren, Ruobing, Espenshade, Peter, Yan, Nieng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387560/
https://ncbi.nlm.nih.gov/pubmed/25771684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.32
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