Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition

The sterol regulatory element-binding protein (SREBP) and SREBP cleavage-activating protein (SCAP) are central players in the SREBP pathway, which control the cellular lipid homeostasis. SCAP binds to SREBP through their carboxyl (C) domains and escorts SREBP from the endoplasmic reticulum to the Go...

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Detaylı Bibliyografya
Yayımlandı:Cell Res
Asıl Yazarlar: Gong, Xin, Li, Jingxian, Shao, Wei, Wu, Jianping, Qian, Hongwu, Ren, Ruobing, Espenshade, Peter, Yan, Nieng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387560/
https://ncbi.nlm.nih.gov/pubmed/25771684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.32
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