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Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP

The endoplasmic reticulum membrane protein SREBP cleavage-activating protein (Scap) senses sterols and regulates activation of sterol-regulatory element binding proteins (SREBPs), membrane-bound transcription factors that control lipid homeostasis in fission yeast and mammals. Transmembrane segments...

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Bibliografiska uppgifter
Huvudupphovsmän: Hughes, Adam L., Stewart, Emerson V., Espenshade, Peter J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515523/
https://ncbi.nlm.nih.gov/pubmed/18503029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800207-JLR200
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