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Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP
The endoplasmic reticulum membrane protein SREBP cleavage-activating protein (Scap) senses sterols and regulates activation of sterol-regulatory element binding proteins (SREBPs), membrane-bound transcription factors that control lipid homeostasis in fission yeast and mammals. Transmembrane segments...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2515523/ https://ncbi.nlm.nih.gov/pubmed/18503029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800207-JLR200 |
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