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Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member

Sre1, the fission yeast sterol regulatory element binding protein, is an endoplasmic reticulum membrane-bound transcription factor that responds to changes in oxygen-dependent sterol synthesis as an indirect measure of oxygen availability. Under low oxygen, Sre1 is proteolytically cleaved and the re...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hughes, Bridget T, Espenshade, Peter J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396400/
https://ncbi.nlm.nih.gov/pubmed/18418381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.83
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