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Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member

Sre1, the fission yeast sterol regulatory element binding protein, is an endoplasmic reticulum membrane-bound transcription factor that responds to changes in oxygen-dependent sterol synthesis as an indirect measure of oxygen availability. Under low oxygen, Sre1 is proteolytically cleaved and the re...

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Bibliografski detalji
Glavni autori: Hughes, Bridget T, Espenshade, Peter J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396400/
https://ncbi.nlm.nih.gov/pubmed/18418381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.83
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