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Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member
Sre1, the fission yeast sterol regulatory element binding protein, is an endoplasmic reticulum membrane-bound transcription factor that responds to changes in oxygen-dependent sterol synthesis as an indirect measure of oxygen availability. Under low oxygen, Sre1 is proteolytically cleaved and the re...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396400/ https://ncbi.nlm.nih.gov/pubmed/18418381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.83 |
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