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Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast

Sre1, the fission yeast sterol regulatory element-binding protein, is an ER membrane-bound transcription factor that controls adaptation to low oxygen growth. Under low oxygen, Sre1 is proteolytically cleaved and the N-terminal transcription factor domain (Sre1N) is released from the membrane and en...

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Autori principali: Lee, Chih-Yung S, Stewart, Emerson V, Hughes, Bridget T, Espenshade, Peter J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634736/
https://ncbi.nlm.nih.gov/pubmed/19158663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.271
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