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Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA bindingand degradation

Cells adapt to changes in ambient oxygen by changing their gene expression patterns. In fission yeast, the sterol regulatory element–binding protein Sre1 is proteolytically cleaved under low oxygen, and its N-terminal segment (Sre1N) serves as a hypoxic transcription factor. When oxygen is present,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Porter, Joshua R., Lee, Chih-Yung S., Espenshade, Peter J., Iglesias, Pablo A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Cell Biology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442422/
https://ncbi.nlm.nih.gov/pubmed/22833559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-06-0451
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