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Ergosterol Regulates Sterol Regulatory Element Binding Protein (SREBP) Cleavage in Fission Yeast
In fission yeast, the endoplasmic reticulum membrane-bound proteins Sre1 and Scp1, orthologs of mammalian sterol regulatory element binding protein (SREBP) and Scap, monitor sterol synthesis as an indirect measure of oxygen supply. When cellular oxygen levels are low, sterol synthesis is inhibited,...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003404/ https://ncbi.nlm.nih.gov/pubmed/20959444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.144337 |
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