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Structural Requirements for Sterol Regulatory Element-binding Protein (SREBP) Cleavage in Fission Yeast

Sterol regulatory element-binding proteins (SREBPs) are central regulators of cellular lipid synthesis and homeostasis. Mammalian SREBPs are proteolytically activated and liberated from the membrane by Golgi Site-1 and Site-2 proteases. Fission yeast SREBPs, Sre1 and Sre2, employ a different mechani...

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Autores principales: Chong, Rockie, Espenshade, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711301/
https://ncbi.nlm.nih.gov/pubmed/23729666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482224
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