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Structural Requirements for Sterol Regulatory Element-binding Protein (SREBP) Cleavage in Fission Yeast
Sterol regulatory element-binding proteins (SREBPs) are central regulators of cellular lipid synthesis and homeostasis. Mammalian SREBPs are proteolytically activated and liberated from the membrane by Golgi Site-1 and Site-2 proteases. Fission yeast SREBPs, Sre1 and Sre2, employ a different mechani...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711301/ https://ncbi.nlm.nih.gov/pubmed/23729666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482224 |
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