The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

The positive transcription elongation factor b (P-TEFb) (CDK9/cyclin T (CycT)) promotes mRNA transcriptional elongation through phosphorylation of elongation repressors and RNA polymerase II. To understand the regulation of a transcriptional CDK by its cognate cyclin, we have determined the structur...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Baumli, Sonja, Lolli, Graziano, Lowe, Edward D, Troiani, Sonia, Rusconi, Luisa, Bullock, Alex N, Debreczeni, Judit É, Knapp, Stefan, Johnson, Louise N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486423/
https://ncbi.nlm.nih.gov/pubmed/18566585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.121
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados