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Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5)

Spinophilin is a protein that binds to protein phosphatase-1 and actin and modulates excitatory synaptic transmission and dendritic spine morphology. We have identified three sites phosphorylated by ERK2 (Ser-15 and Ser-205) and cyclin-dependent PK 5 (Cdk5) (Ser-17), within the actin-binding domain...

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Bibliografiske detaljer
Main Authors: Futter, Marie, Uematsu, Ken, Bullock, Stewart A., Kim, Yong, Hemmings, Hugh C., Nishi, Akinori, Greengard, Paul, Nairn, Angus C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC552943/
https://ncbi.nlm.nih.gov/pubmed/15728359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409802102
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