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Binding to DNA of the RNA-polymerase II C-terminal domain allows discrimination between Cdk7 and Cdk9 phosphorylation

The C-terminal domain (CTD) of RNA polymerase II regulates transcription through spatially and temporally coordinated events. Previous work had established that the CTD binds DNA but the significance of this interaction has not been determined. The present work shows that the CTD binds DNA in its un...

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Bibliografiska uppgifter
Huvudupphovsman: Lolli, Graziano
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651791/
https://ncbi.nlm.nih.gov/pubmed/19136461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1061
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