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SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription
SIRT7 is an NAD(+)-dependent protein deacetylase that regulates cell growth and proliferation. Previous studies have shown that SIRT7 is required for RNA polymerase I (Pol I) transcription and pre-rRNA processing. Here, we took a proteomic approach to identify novel molecular targets and characteriz...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389538/ https://ncbi.nlm.nih.gov/pubmed/28426094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx053 |
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