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The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II

The human immunodeficiency virus encodes the transcriptional transactivator Tat, which binds to the transactivation response (TAR) RNA stem–loop in the viral long terminal repeat (LTR) and increases rates of elongation rather than initiation of transcription by RNA polymerase II (Pol II). In this st...

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Main Authors: Cujec, Thomas P., Okamoto, Hiroshi, Fujinaga, Koh, Meyer, Jon, Chamberlin, Holly, Morgan, David O., Peterlin, B. Matija
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC316603/
https://ncbi.nlm.nih.gov/pubmed/9334327
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