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The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II

The human immunodeficiency virus encodes the transcriptional transactivator Tat, which binds to the transactivation response (TAR) RNA stem–loop in the viral long terminal repeat (LTR) and increases rates of elongation rather than initiation of transcription by RNA polymerase II (Pol II). In this st...

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Detalhes bibliográficos
Main Authors: Cujec, Thomas P., Okamoto, Hiroshi, Fujinaga, Koh, Meyer, Jon, Chamberlin, Holly, Morgan, David O., Peterlin, B. Matija
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316603/
https://ncbi.nlm.nih.gov/pubmed/9334327
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