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The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II

The human immunodeficiency virus encodes the transcriptional transactivator Tat, which binds to the transactivation response (TAR) RNA stem–loop in the viral long terminal repeat (LTR) and increases rates of elongation rather than initiation of transcription by RNA polymerase II (Pol II). In this st...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Cujec, Thomas P., Okamoto, Hiroshi, Fujinaga, Koh, Meyer, Jon, Chamberlin, Holly, Morgan, David O., Peterlin, B. Matija
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1997
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9334327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.20.2645
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