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Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target

Deregulation of cyclin-dependent kinases (CDKs) has been associated with many cancer types and has evoked an interest in chemical inhibitors with possible therapeutic benefit. While most known inhibitors display broad selectivity towards multiple CDKs, recent work highlights CDK9 as the critical tar...

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Detalhes bibliográficos
Main Authors: Kryštof, Vladimír, Baumli, Sonja, Fürst, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382371/
https://ncbi.nlm.nih.gov/pubmed/22571657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138161212800672750
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