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Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target

Deregulation of cyclin-dependent kinases (CDKs) has been associated with many cancer types and has evoked an interest in chemical inhibitors with possible therapeutic benefit. While most known inhibitors display broad selectivity towards multiple CDKs, recent work highlights CDK9 as the critical tar...

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Détails bibliographiques
Auteurs principaux: Kryštof, Vladimír, Baumli, Sonja, Fürst, Robert
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382371/
https://ncbi.nlm.nih.gov/pubmed/22571657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138161212800672750
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