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Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target

Deregulation of cyclin-dependent kinases (CDKs) has been associated with many cancer types and has evoked an interest in chemical inhibitors with possible therapeutic benefit. While most known inhibitors display broad selectivity towards multiple CDKs, recent work highlights CDK9 as the critical tar...

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Detalles Bibliográficos
Main Authors: Kryštof, Vladimír, Baumli, Sonja, Fürst, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Bentham Science Publishers 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382371/
https://ncbi.nlm.nih.gov/pubmed/22571657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138161212800672750
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