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Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target

Deregulation of cyclin-dependent kinases (CDKs) has been associated with many cancer types and has evoked an interest in chemical inhibitors with possible therapeutic benefit. While most known inhibitors display broad selectivity towards multiple CDKs, recent work highlights CDK9 as the critical tar...

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Bibliografiska uppgifter
Huvudupphovsmän: Kryštof, Vladimír, Baumli, Sonja, Fürst, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: Bentham Science Publishers 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382371/
https://ncbi.nlm.nih.gov/pubmed/22571657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138161212800672750
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